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More about Ergothoineine

The Importance of L-Ergothioneine or EGT in Our Formulations

In our quest to provide the most effective skincare products, we have incorporated L-Ergothioneine into our Pro-Age Marine Collagen Boost Night Cream and Advanced Vitamin C Serum.

This decision is backed by extensive research that highlights the incredible benefits of this ingredient. L-Ergothioneine is a potent antioxidant naturally found in the human body's cellular makeup. However, due to modern diets and lifestyles, supplementing it in our formulations has become crucial.

When it comes to skin health, ultraviolet (UV) irradiation is a significant environmental factor that can lead to various skin conditions, including photo-aging and cancer.

UVA/B rays penetrate the skin, reaching the cells and being absorbed by proteins, lipids, and nuclear/mitochondrial DNA. This absorption triggers a cascade of oxidative events, resulting in the progressive deterioration of cellular structure and function.

Mitochondria, responsible for generating around 90% of the cellular energy through oxidative phosphorylation, produce reactive oxygen species (ROS) during this process.

While mitochondria have antioxidants to counteract ROS production, some manage to escape and cause damage to mitochondrial DNA, proteins, and lipids. Mitochondrial DNA (mtDNA) is distinct from nuclear DNA and is more susceptible to damage. As a result, mtDNA mutations and deletions accumulate in various tissues during the aging process.

These mutations occur due to the proximity of mtDNA to the inner membrane, where reactive oxygen species are continuously generated in the electron transport chain. Photoaged skin is particularly affected by increased mitochondrial genome mutations, which occur more frequently with prolonged sun exposure.

L-Ergothioneine, also known as EGT, is a unique sulfur-containing derivative of histidine, an amino acid.

It serves as a vital component of the cellular antioxidant defense system. EGT acts as a scavenger for hydroxyl and peroxynitrite radicals, as well as the superoxide anion radical and singlet oxygen.

Scientific studies have shown that EGT is a more powerful antioxidant than coenzyme Q(10) or idebenone due to its superior efficiency in directly scavenging free radicals and protecting cells from UV-induced reactive oxygen species.

In line with this research, Kalōnology's Pro Age Marine Collagen Boost Night Cream and Advanced Vitamin C Serum contain optimal daily levels of L-Ergothioneine.

The inclusion of this ingredient is supported by its rich history and ten scientifically proven benefits. These benefits are backed by reliable sources of data, ensuring the credibility of the claims. It is important to note any potential side effects associated with the ingredient as well.

Introducing Kalōnology's Pro Age Marine Collagen Boost Night Cream,

a skincare product meticulously designed to enhance collagen synthesis, reduce the appearance of fine lines and wrinkles, and facilitate cellular DNA repair while you sleep.

The cream combines optimal concentrations of active ingredients into one product, harnessing the power of 100% natural, sustainably sourced bioactive ingredients.

Pro Age Marine Collagen Boost Night Cream is enriched with skin-firming extracts, peptides, cellular DNA repairing enzymes, and a potent blend of antioxidants.

One of the unique ingredients in this cream is Perfluorodecalin & Perfluorohexane, a powerful oxygenating formulation with a 5% concentration. This formulation swiftly penetrates the skin, oxygenating cells, neutralizing carbon dioxide, and expediting cellular renewal. Clinically proven, this liquid oxygenating formulation reduces the appearance of wrinkles by up to 15%.

Laminaria & Porphyra algae extracts are also incorporated into the cream to provide skin-firming properties and strengthen the connective tissue matrix, resulting in gentle firmness of the skin.

L-Ergothioneine plays another crucial role as an active ingredient in this formulation. It catalyzes oxygen consumption in the mitochondria, optimizing metabolism and acting as a co-antioxidant. By doing so, L-Ergothioneine reduces stress and defends cellular DNA, contributing to the overall health and vitality of the skin.

Additionally, the cream features Arctic Peptides, a powerful complex of peptides extracted from Chondrus Crispus Algae found in the pristine waters north of the Arctic Circle.

These peptides have undergone rigorous clinical testing and have been proven to effectively block the by-products of Glycation, a major contributor to premature aging of the skin.

Alongside these peptides, the cream incorporates L-Citrulline & L-Arginine, Taurine, and Floridoside, further enhancing its anti-aging properties.

Hexapeptide-11, another active ingredient, has been scientifically proven to improve skin elasticity by 35% and support the connective tissue matrix over a 28-day period. Hyaluronic Acid, known for its exceptional moisturizing abilities, actively hydrates the skin, keeping it supple and plump.

The cream also harnesses the power of Photolyase, a scientifically proven ingredient capable of reducing and repairing UV A & B-related DNA damage. This ingredient not only repairs damage but also induces apoptosis in problematic cells, inhibiting their progression. Furthermore, it has shown potential in reversing the effects of overexposure to UV radiation.

To amplify the antioxidant properties of the cream, it contains Astaxanthin, an extract derived from Haematococcus Algae. This powerful antioxidant reduces inflammation and redness, outperforming Ascorbic Acid by 65 times and Co-Q10 by 800 times in recycling Vitamin C.

Additionally, Palmitoleic Acid, extracted from Nannochloropsis Algae, acts as an anti-inflammatory agent rich in Omega-3 fatty acids (30%), Omega-7 (60%), and Phytosterols (10%).

Pro Age Marine Collagen Boost Night Cream from Kalōnology stands out as one of the premier pro-collagen marine creams available for all skin types. Its carefully selected natural ingredients work synergistically to improve collagen production, reduce the appearance of wrinkles, and repair UV damage while you sleep.

Indulge your skin with the nourishment it deserves by incorporating Kalōnology's Pro Age Marine Collagen Boost Night Cream into your skincare routine. Your skin will thank you.

Kalōnology is only available on their website where they are currently offering a 20% discount on your introductory purhcase. Simply add the code GETLESS20% during checkout while stocks last - they ship Worldwide too!

Here are the ten scientifically proven benefits of L-Ergothioneine, along with their respective sources:

  1. Powerful Antioxidant Activity:

  2. Scavenges Free Radicals:

  3. Protects Cells from UV-Induced Reactive Oxygen Species:

  4. Supports Mitochondrial Function:

  5. Reduces Oxidative Damage to DNA, Proteins, and Lipids:

  6. Enhances Antioxidant Defense System:

  7. Supports Skin Health and Anti-Aging:

  8. Protects Against Photo-Aging:

  9. Maintains Mitochondrial DNA Integrity:

  10. Supports Brain Health:

These studies provide scientific evidence for the various benefits associated with L-Ergothioneine supplementation.

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