Photolyase (a type of DNA repairing enzyme) is used for the reduction of symptoms related to Rosacea, Melanoma - and even has the ability to reverse damage to DNA.
Over 40 years of research has gone into studying Photolyase as a DNA repairing enzyme in liposomes for the treatment of UV A & B damage to the skin.
The mechanisms behind the enzymes' ability to penetrate the skin, reach damaged DNA, and stimulate its repair have been studied extensively, their efficacy and the safety profile is well documented and is attractive, with no serious side effects reported in clinical trials.
One of the really exciting applications of Photolyase relates to its ability to reduce the symptoms of Rosacea. Rosacea is a chronic skin condition characterised by redness, inflammation, and the formation of pimples and bumps.
Out of interest, sun overexposure is known to worsen the symptoms of Rosacea.
DNA repair is an ongoing process that occurs within the dynamic cell metabolism, including time-sensitive transcription of potentially damaged DNA strands. It's the rate of damage removal, not the absolute level of repair, that explains why enhanced repair has such a significant impact on cellular responses to UV radiation.
Clinical studies involving hundreds of subjects have reported the prevention of AKs (actinic keratoses) and skin cancer through enhanced DNA repair. This supports the theory that DNA damage can lead to mutations, which in rare cases, result in malignant transformation.
However, the regression of pre-existing AKs and the observed benefits in just weeks and months has been surprising. This suggests that sun damage to the skin creates an environment that allows for the growth of transformed cells, possibly by impairing immune surveillance.
These findings suggest that enhancing DNA repair may improve the signs of photo-aging and prevent skin cancers, including rosacea. Although the data is not yet conclusive, this is an exciting area for future research to establish the role of DNA damage in skin aging and its central role in the initiation and promotion of skin conditions, such as rosacea.
The use of photolyase in advanced skin care formulations is a promising avenue for the treatment of sun damage and reducing the signs of rosacea. With its attractive safety profile and the potential for measurable benefits, photolyase is worth exploring for those looking to improve the health and appearance of their skin.
Kalōnology's Pro Age Marine Collagen Boost Night Cream is a scientifically advanced skincare solution which harnesses the power of natural, sustainably sourced ingredients to reduce the signs of aging and even has the ability to repair damaged skin over time.
This powerful anti-wrinkle cream is packed with optimal concentrations of active ingredients to boost collagen synthesis, hydrate the skin, and repair cellular DNA while you sleep.
The cream features a unique blend of skin-firming extracts, peptides, antioxidants, and cellular DNA repairing enzymes, including Photolyase, which reduces and repairs UV A & B related DNA damage. Photolyase works by inducing apoptosis in problematic cells, inhibiting their progression, and reversing the effects of damage from over-exposure.
The cream also contains Perfluorodecalin & Perfluorohexane, an oxygenating formulation that instantly penetrates the skin to oxygenate cells, neutralise carbon dioxide, and speed up cellular renewal.
Clinical studies have shown that this powerful ingredient can reduce the appearance of wrinkles by up to 15%.
Arctic Peptides, a complex of peptides extracted from Chondrus Crispus Algae, blocks the by-products of Glycation, a major source of premature aging, while Hexapeptide-11 has been shown to improve skin elasticity and support the connective tissue matrix. Hyaluronic Acid provides active moisturisation, and Astaxanthin, a powerful antioxidant extracted from Haematococcus Algae, also reduces redness and inflammation.
Laminaria & Porphyra algae extracts provide skin-firming benefits, while L-Ergothioneine is an extraordinary dual-action ingredient which optimises metabolism and acts as a co-antioxidant.
Kalōnology's Pro Age Marine Collagen Boost Night Cream also includes Palmitoleic Acid, an anti-inflammatory extract from Nannochloropsis Algae that is rich in Omega-3 and Omega-7 fatty acids and Phytosterols.
Kalōnology's Pro Age Marine Collagen Boost Night Cream is a top-of-the-line pro collagen marine cream that improves collagen production, reduces the appearance of wrinkles, and repairs skin damage while you sleep. With its unique blend of natural, sustainably sourced ingredients, this cream is the perfect addition to your skincare routine.
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