This site has limited support for your browser. We recommend switching to Edge, Chrome, Safari, or Firefox.

Get 20% off your purchase today! Add GETLESS20% during checkout! Available to UK and International clients (please confirm we ship to your Country by selecting your currency in the footer section below)

Why apply Palmitoleic Acid to the skin?

The Benefits of Palmitoleic Acid in Advanced Skin Care formulations:

Hyperpigmentation, caused by a variety of factors such as exposure to ultraviolet light, genetics, and other causes, is a common skin concern.

In an effort to find new skin lightening ingredients, scientists have investigated the effects of palmitoleic acid on melanin formation. A recent study has shown that palmitoleic acid effectively down-regulates melanin content in a dose-dependent pattern.

The study performed Western blotting for key melanogenic enzymes, including tyrosinase, tyrosinase-related protein-1 (TRP-1), TRP-2, and microphthalmia-associated transcription factor (MITF). Results indicated that Palmitoleic acid was able to inhibit the expressions of tyrosinase, TRP-2, and MITF in a dose-dependent manner. However, it did not inhibit TRP-1 expression.

In addition to its anti-melanogenic properties, the study also determined the cytotoxicity of Palmitoleic acid using a human cell line. Results showed that Palmitoleic acid was non-toxic at 500 muM, making it a promising candidate for modern, advanced skin care formulations.

The study suggests that Palmitoleic acid is an effective ingredient in the treatment of hyperpigmentation disorders. Its ability to down-regulate melanin content and inhibit key melanogenic enzymes, combined with its non-toxic effects, make it a valuable ingredient in premium skin care formulations.

If you are looking to address hyperpigmentation or improve the overall health of your skin, consider incorporating products containing palmitoleic acid into your routine.

Kalōnology include this ingredient in their Pro Age Marine Collagen Boost Night Cream which is sustainably sourced from blue and green algae plants. 

Kalōnology Pro Age Marine Collagen Boost Night Cream, The Benefits of Palmitoleic Acid, night cream, anti wrinkle, anti aging moisturiser

Kalōnology Responsible Skin Care are offering 20% off your first purchase when you buy directly on

They ship Worldwide but please confirm they ship to your exact location before placing your order. Add GETLESS20% during checkout. 

Leave a comment

Please note, comments must be approved before they are published


No more products available for purchase

Your cart is currently empty.